SACRAHAUS L-Glutamine Vegan Capsules

L-glutamine is the primary fuel for enterocytes (gut-lining cells). The most rigorous human trial — Zhou et al. in Gut — showed clinically meaningful improvement in post-infectious IBS-D specifically.

Caveat: Strong evidence is in post-infectious IBS-D; benefit in healthy adults or other GI conditions is less established.

• RCTGut (BMJ) · 2019n = 106

  Randomised placebo-controlled trial of dietary glutamine supplements for postinfectious irritable bowel syndrome

  Zhou Q, Verne ML, Fields JZ, et al.

  "Oral glutamine therapy significantly reduced IBS-Symptom Severity Score (≥50-point reduction) in patients with postinfectious IBS-D and increased intestinal permeability."

  Landmark RCT: oral glutamine produced clinically meaningful symptom improvement in postinfectious IBS-D.

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• MECHANISTIC STUDYJPEN. Journal of Parenteral and Enteral Nutrition · 2016

  Glutamine Restores Tight Junction Protein Claudin-1 Expression in Colonic Mucosa of Patients With Diarrhea-Predominant IBS

  Bertrand J, Ghouzali I, Guérin C, et al.

  "Glutamine restored colonic claudin-1 tight-junction protein expression in IBS-D patients, providing a mechanistic basis for the symptom improvements observed clinically."

  Mechanistic study: explains how glutamine works — by restoring tight-junction proteins in the gut lining.

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